hfl 1 cells (ATCC)
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96
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ATCC
hfl 1 cells
Hfl 1 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 642 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hfl+1+cells/HFL1/pm42296933-205-0-5
Average 96 stars, based on 642 article reviews
Hfl 1 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 642 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/hfl+1+cells/HFL1/pm42296933-205-0-5
Average 96 stars, based on 642 article reviews
hfl 1 cells - by Bioz Stars,
2026-09
96/100 stars
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other:Article Title: Development of Adamantane-based hydrophobic tags targeting anaplastic lymphoma kinase with enhanced antitumor activities. Article Snippet: Anaplastic lymphoma kinase (ALK) has emerged as a critical molecular target for therapeutic intervention in various malignancies, with a particular focus on non-small cell lung cancer (NSCLC) and anaplastic large-cell lymphomas (ALCLs).. In this work, we utilized the hydrophobic tagging (HyT) strategy to design and synthesize a series of novel ALK-targeting degraders, which were constructed by linking the derivative A3 based on ALK inhibitor alectinib to a HyT fragment adamantane via various customized linkers.. The most promising compound, H7, demonstrated potent ALK degradation activity both in vitro and in vivo, along with potent antiproliferative effects in ALK-dependent cell lines, while showing minimal cytotoxicity in cells lacking ALK fusion proteins. Cell Culture:Article Title: Transcription factor ID3 promotes fibroblast differentiation and proliferation in lung fibrosis through augmenting the TGF-β signaling pathway. Article Snippet: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease characterized by myofibroblast activation, accumulation, and excessive extracellular matrix deposition.. Although fibroblast activation and proliferation are central drivers of fibrogenesis, the molecular regulators coordinating these processes remain poorly defined.. This study investigated fibroblast lineage progression using single-cell RNA-sequencing data from fibroblast-enriched populations in bleomycin-induced mouse models and human IPF samples. |